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Graphical presentation of CX-5461-mediated activation on the cytosolic DNA sensing pathway. cGAS binding to the cytosolic DNA activates the secondary messenger 2,3-cGAMP utilizing cGAS being a catalyst. Activated STING buds from the ER moving on the perinuclear Golgi, where by it's palmitoylated.The location is secure. The https:// makes certain th
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